THE COMT GENE: ASSOCIATION WITH SCHIZOPHRENIA AND AGGRESSIVE BEHAVIOR
Zainullina A. 1, Gaysina D. 1, Jurjev E. 1, Ghabdulhatov R. 2, Gumerova R.3, Khusnutdinova E.1
*Corresponding Author: Mrs. Aigul Zainullina, Department of Human Genomic, Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences; 69 Octyabrya Avenue, Ufa, 450054, Russia. Telephone number: +7 3472 356088. Fax number: +7 3472 356100. E-mail: aigul_zainullina@mail.ru, dgaisina@mail.ru
page: 51

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14. Kolter M, Barak P, Cohen H, Averbuch IE, Grinshpoon, A Gritsenko I., Nemanov L, Ebstein RP. Homicidal behavior in schizophrenia associated with a genetic polymorphism determining low catechol O-methyltransferase (COMT) activity. Am J Med Genet. 1999; 88(6):628-633.

15. Nolan KA, Volavka J, Czobor P, Cseh A, Lachman H, Saito T, Tiihonen J, Putkonen A, Hallikainen T, Kotilainen I, Rasanen P, Isohanni M, Jarvelin MR, Karvonen MK. Suicidal behavior in patients with schizophrenia is related to COMT polymorphism Psychiatr Genet 2000; 10(3): 117-124.

16. Millikan RC, Pittman GS, Tse C-KJ et al. Catechol-O-methyltransferase and breast cancer risk. Cancerogenesis 1998; 19(11):1943-1947.

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19. Jones G, Zammit S, Norton N, Hamshere ML, Jones SJ, Milham C, Sanders RD, McCarthy GM, Jones LA, Cardno AG, Gray M, Murphy KC, Owen MJ,. Aggressive behaviour in patients with schizophrenia is associated with catechol-O-methyltransferase genotype. Br J Psychiatry 2001; 179: 351–355.

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