THE COMT GENE: ASSOCIATION WITH SCHIZOPHRENIA AND AGGRESSIVE BEHAVIOR
Zainullina A. 1, Gaysina D. 1, Jurjev E. 1, Ghabdulhatov R. 2, Gumerova R.3, Khusnutdinova E.1
*Corresponding Author: Mrs. Aigul Zainullina, Department of Human Genomic, Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences; 69 Octyabrya Avenue, Ufa, 450054, Russia. Telephone number: +7 3472 356088. Fax number: +7 3472 356100. E-mail: aigul_zainullina@mail.ru, dgaisina@mail.ru
page: 51

REFERENCES

1. Price-Evans DA. Genetic Factors in Drug Therapy: Clinical and Molecular Pharmacogenetics. Cambridge University Press, Cambridge. 1993.

2. Grossman MH, Emanuel BS, Budarf ML. Chromosomal mapping of the human catechol-O-methyltransferase gene to 22q11.1-q11.2. Genomics 1992; 12(4): 822-825.

3. Lachman HM, Nolan KA, Mohr P, Saito T, Volavka J. Association between catechol-O-methyltransferase genotype and violence in schizophrenia and schizoaffective disorder. Am. J. Psychiatry 1998; 155(6): 835837.

4. Aksoy S, Klener J, Weinshilboum RM. Catechol-O-methyltransferase pharmacogenetics: photoaffinity labelling and Western blot analysis of human liver samples. Pharmacogenetics 1993; 3(2): 116122.

5. Palmatier MA, Kang AM, Kidd KK. Global variation in the frequencies of functionally different catechol-O-methyltrans-ferase alleles. Biol Psych 1999; 46(4): 557567.

6. Park TW, Yoon KS, Kim JH , Park WY, Hirvonen A, KangD. Functional catechol-O-methyltransferase gene polymorphism andsusceptibility to schizophrenia European Neuropsychopharmacology 2002; 12(4): 299 303.

7. Wonodi I, Stine OC, Mitchell BD, Buchanan RW, Thaker GK. Association between Val108/158 Met polymorphism of the COMT gene and schizophrenia. Am J Med Genet 2003; 120B(1): 47-50.

8. Li T, Vallada H, Curtis D, Arranz M, Xu K, Cai G, Deng H, Liu J, Murray R, Liu X, Collier DA. Catechol-O-methyltransferase Val 158 Met polymorphism: frequency analysis in Han Chinese subjects and allelic association of the low activity allele with bipolar antisocial behavior. Pharmacogenetics 1997; 7(5): 349-53.

9. Ohara K, Nagai M, Suzuki Y, Ochiai M, Ohara K. No association between anxiety disorders and catechol-O-methyltransferase polymorphism. Psychiatry Res 1998; 80(2): 145-148.

10. Rotondo A, Mazzanti C, Dell'Osso L, Rucci P, Sullivan P, Bouanani S, Gonnelli C, Goldman D, Cassano GB.Catechol o-methyltransferase, serotonin transporter, and tryptophan hydroxylase gene polymorphisms in bipolar disorder patients with and without comorbid panic disorder. Am J Psychiatry 2002; 159(1): 23-29.

11. Woo JM, Yoon KS, Yu BH.Catechol O-methyltransferase genetic polymorphism in panic disorder. Am J Psychiatry 2002; 159(10):1785-1787.

12. Strous RD, Bark, N, Parsia SS, Volavka J, Lachman HM, Analysis of a functional catechol-O-methyltransferase gene polymor phism in schizophrenia: evidence for association with aggressive and antisocial behavior. Psychiatry Res 1997; 69(2-3): 7177.

13. Strous RD, Nolan KA, Lapidus R, Diaz L, Saito T, Lachman HM. Aggressive behavior in schizophrenia is associated with the low enzyme activity COMT polymorphism: a replication study. Am J Med Genet 2003; 120B(1): 29-34.

14. Kolter M, Barak P, Cohen H, Averbuch IE, Grinshpoon, A Gritsenko I., Nemanov L, Ebstein RP. Homicidal behavior in schizophrenia associated with a genetic polymorphism determining low catechol O-methyltransferase (COMT) activity. Am J Med Genet. 1999; 88(6):628-633.

15. Nolan KA, Volavka J, Czobor P, Cseh A, Lachman H, Saito T, Tiihonen J, Putkonen A, Hallikainen T, Kotilainen I, Rasanen P, Isohanni M, Jarvelin MR, Karvonen MK. Suicidal behavior in patients with schizophrenia is related to COMT polymorphism Psychiatr Genet 2000; 10(3): 117-124.

16. Millikan RC, Pittman GS, Tse C-KJ et al. Catechol-O-methyltransferase and breast cancer risk. Cancerogenesis 1998; 19(11):1943-1947.

17. Thomson G. A review of theoretical aspects of HLA and Disease associations. Theor Popul Biol 1981; 20(2): 168.

18. Tehrani JA, Brennan PA, Hodgins S, Mednick SA. Mental illness and criminal violence. Soc PsychiatryPsychiatr Epidemiol 1998; 33(1): 81-85

19. Jones G, Zammit S, Norton N, Hamshere ML, Jones SJ, Milham C, Sanders RD, McCarthy GM, Jones LA, Cardno AG, Gray M, Murphy KC, Owen MJ,. Aggressive behaviour in patients with schizophrenia is associated with catechol-O-methyltransferase genotype. Br J Psychiatry 2001; 179: 351355.

19. Chen CH, Lee YR, Wei FC, Koong FJ, Hwu HG, Hsiao KJ. Association study of NlaIII and MspI genetic polymorphism of catechol-O-methyltransferase gene and susceptibility to schizophrenia. Biol. Psychiatry 1997; 41(9): 985987.

20. Liou YJ, Tsai SJ, Hong CJ, Wang YC, Lai IC Association analysis of a functional catechol-o-methyltransferase gene polymorphism in schizophrenic patients in Taiwan. Neuropsychobiology. 2001;43(1):11-14.

 




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