APOLIPOPROTEIN(a) POLYMORPHISMS IN A HEALTHY MACEDONIAN POPULATION Tosheska K*, Labudovic D, Alabakovska S, Todorova B *Corresponding Author: Katerina Tosheska K, MD, MSc., Department of Medical and Experimental Biochemistry, Faculty of Medicine, 50 Divizija 6, 1000 Skopje, Republic of Macedonia; Tel: +389-2-3217-303; Fax: +389-2-3230-431; E-mail: tosheskatrajkovska@yahoo.com
page: 49
|
REFERENCES
1. Kronenberg F, Steinmetz A, Kostner GM, Dieplinger H. Lipoprotein(a) in health and disease. Crit Rev Clin Lab Sci 1996; 33(6): 495-543.
2. Kostner KM, Avogaro P, Cazzolato G, Marth E, Bittolo-Bon G, Qunici GB. Lipoprotein (a) and the risk for myocardial infarction. Atherosclerosis 1981; 38(1-2): 51-61.
3. Dahlen G. The pre-b1 lipoprotein phenomenon in relation to serum cholesterol and trygliceride levels, the Lp(a) lipoprotein and coronary heart disease. Acta Med Scand Suppl 1974; 570: 1-45.
4. Berg K. A new serum type in man – the Lp system. Acta Pathol 1963; 59: 369-382.
5. Gaubatz JW, Heideman C, Gotto AM, Morrisett JD, Dahlen GH. Human plasma lipoprotein(a): structural properties. J Biol Chem 1983; 258(7): 4582-4589.
6. Ehnholm C, Garoff H, Renkonen O, Simons K. Protein and carbohydrate composition of Lp(a)lipoprotein from human plasma. Biochemistry 1972; 11(17) 3229-3232.
7. Utermann G, Weber W. Protein composition of Lp(a) lipoprotein from human plasma. FEBS Lett 1983; 154(2): 357-361.
8. Harvie NR, Schultz JS. Studies of Lp-lipoprotein as a quantitative genetic trait. Proc Natl Acad Sci USA 1970; 66(1): 99-103.
9. Kraft HG, Köchl S, Menzel HJ, Sandholzer C, Utermann G. The apolipoprotein (a) gene: a transcribed hypervariable locus controlling plasma lipoprotein(a) concentration. Hum Genet 1992; 90(3): 220-230.
10. McLean JW, Tomlinson JE, Kuang W, Eaton DL, Chen EY, Fless GM, Scanu AM, Lawn RM. cDNA sequence of human apolipoprotein(a) is homologous to plasminogen. Nature 1987; 330(6144): 132-137.
11. Lackner C, Cohen JC, Hobbs HH. Molecular definition of the extreme size polymorphism in apolipoprotein(a). Hum Mol Genet 1993; 2(7): 933-940.
12. Koscinsky ML, Beisiegel, Henne-Bruns D, Eaton DL, Lawn RM. Apolipoprotein (a) size heterogeneity is related to variable number of repeat sequences in its mRNA. Biochemistry 1990; 29(3): 640-644.
13. Scanu AM, Fless GM. Lipoprotein(a). Heterogeneity and biological relevance. J Clin Invest 1990; 85(6): 1709-1715.
14. Utermann G, Menzel HJ, Kraft HG, Duba HC, Kemmler HG, Seitz C. Lp(a) glycoprotein phenotypes. J Clin Invest 1987; 80(2): 458-465.
15. Rainwater DL, Manis GS, VandeBerg JL. Hereditary and dietary effects on apolipoprotein(a) isoforms and Lp(a) in baboons. J Lipid Res 1989; 30(4): 549-558.
16. Sandholzer C, Hallman DM, Saha N, Sigurdsson G, Lackner C, Csaszar A, Boerwinkle E, Utermann G. Effects of the apolipoprotein(a) size polymorphism on the lipoprotein(a) concentration in 7 ethnic groups. Hum Genet 1991; 86(6): 607-614.
17. Gavish D, Azrolan N, Breslow JL. Plasma Lp(a) concentration is inversely correlated with the ratio of kringle IV/kringle V encoding domains in the apo(a) gene. J Clin Invest 1989; 84(6): 2021-2027.
18. Albers JJ, Marcovina MS, Lodge MS. The unique lipoprotein(a): properties and immunochemical measurement. Clin Chem 1990; 36(12): 2019-2026.
19. Boerwinkle E, Leffert CC, Lin J, Lackner C, Chiesa G, Hobbs HH. Apolipoprotein (a) gene accounts for greater than 90% of the variation in plasma lipoprotein (a) concentrations. J Clin Invest 1992; 90(1): 52-60.
20. Mooser V, Mancini FP, Bopp S, Petho-Schramm A, Guerra R, Boerwinkle E, Muller HJ, Hobbs HH. Sequence polymorphism in the apo(a) gene associated with specific levels of Lp(a) in plasma. Hum Mol Genet 1995; 4(2): 173-181.
21. Trommsdorff M, Köchl S, Lingenhel A, Kronenberg F, Delport R, Vermaak H, Lemming L, Klausen IC, Faergeman O, Utermann G. A pentanucleotide repeat polymorphism in the 5’ control region of the apolipoprotein(a) gene is associated with lipoprotein(a) plasma concentrations in Caucasians. J Clin Invest 1995; 96(1): 150-157.
22. Zysow BR, Lindahl GE, Wade DP, Knight Bl, Lawn RM. C/T polymorphism in the 5’ untranslated region of the apolipoprotein(a) gene introduces an upstream ATG and reduces in-vitro translation. Arterioscler Thromb 1995; 15(1): 58-64.
23. Parent X, Hmad Z, Aberer P. Effect of storage of samples at –80°C on the assay of lipoprotein(a) by rate nephelometry (Beckman 360 Array). Ann Biol Clin 1995; 53(1-2): 11-13.
24. Labudovic D, Todorova B, Rainwater D, Alabakovska S, Toseska K. Apoprotein(a) isoform separation by 3-15% gradient SDS denaturating polyacrylamide gel electrophoresis. Maked Med Preg 1999; 53(3-4): 126-131.
25. Labudovic DD, Toseska KN, Alabakovska SB, Todorova BB. Apoprotein(a) phenotypes and plasma lipoprotein(a) concentration in patients with diabetes mellitus. Clin Biochem 2003; 36(7): 545-551.
26. Rainwater D.L. Genetic basis for multimodal relationship between apolipoprotein(a) size and lipoprotein(a) concentration in Mexican-Americans. Atherosclerosis 1995; 115(2): 165-171.
27. Cepellini R, Siniscalo M, Smith CAB. The estimation of gene frequencies in a random-mating population. Ann Hum Genet 1995; 20(2): 97-115.
28. Dempster AP, Laird NM, Rubin DB. Maximum likelihood from incomplete data via the EM algorithm (with discussion). J R Stat Soc B 1977; 39(1): 1-38.
29. Marcovina SM, Zhang ZH, Gaur VP, Albers JJ. Identification of 34 apolipoprotein(a) isoforms: differential expression of apolipoprotein(a) alleles between American blacks and whites. Biochem Biophys Res Commun 1993; 191(3): 1192-1196.
30. Gaubatz JW, Ghanem KI, Guevara J Jr, Nava ML, Patsch W, Morrisett JD. Polymorphic forms of human apolipoprotein(a): inheritance and relationship of their molecular weights to plasma levels of lipoprotein(a). J Lipid Res 1990; 31(4): 603-613.
31. Lackner C, Boerwinkle E, Leffert CC, Rahmig T, Hobbs HH. Molecular basis of apolipoprotein-(a) isoform size heterogeneity as revealed by pulsed-field gel electrophoresis. J Clin Invest 1991; 87(6): 2153-2161.
|
|
|
|
|
Number 26 Number 26 VOL. 26(2), 2023 All in one |
Number 26 VOL. 26(2), 2023 |
Number 26 VOL. 26, 2023 Supplement |
Number 26 VOL. 26(1), 2023 |
Number 25 VOL. 25(2), 2022 |
Number 25 VOL. 25 (1), 2022 |
Number 24 VOL. 24(2), 2021 |
Number 24 VOL. 24(1), 2021 |
Number 23 VOL. 23(2), 2020 |
Number 22 VOL. 22(2), 2019 |
Number 22 VOL. 22(1), 2019 |
Number 22 VOL. 22, 2019 Supplement |
Number 21 VOL. 21(2), 2018 |
Number 21 VOL. 21 (1), 2018 |
Number 21 VOL. 21, 2018 Supplement |
Number 20 VOL. 20 (2), 2017 |
Number 20 VOL. 20 (1), 2017 |
Number 19 VOL. 19 (2), 2016 |
Number 19 VOL. 19 (1), 2016 |
Number 18 VOL. 18 (2), 2015 |
Number 18 VOL. 18 (1), 2015 |
Number 17 VOL. 17 (2), 2014 |
Number 17 VOL. 17 (1), 2014 |
Number 16 VOL. 16 (2), 2013 |
Number 16 VOL. 16 (1), 2013 |
Number 15 VOL. 15 (2), 2012 |
Number 15 VOL. 15, 2012 Supplement |
Number 15 Vol. 15 (1), 2012 |
Number 14 14 - Vol. 14 (2), 2011 |
Number 14 The 9th Balkan Congress of Medical Genetics |
Number 14 14 - Vol. 14 (1), 2011 |
Number 13 Vol. 13 (2), 2010 |
Number 13 Vol.13 (1), 2010 |
Number 12 Vol.12 (2), 2009 |
Number 12 Vol.12 (1), 2009 |
Number 11 Vol.11 (2),2008 |
Number 11 Vol.11 (1),2008 |
Number 10 Vol.10 (2), 2007 |
Number 10 10 (1),2007 |
Number 9 1&2, 2006 |
Number 9 3&4, 2006 |
Number 8 1&2, 2005 |
Number 8 3&4, 2004 |
Number 7 1&2, 2004 |
Number 6 3&4, 2003 |
Number 6 1&2, 2003 |
Number 5 3&4, 2002 |
Number 5 1&2, 2002 |
Number 4 Vol.3 (4), 2000 |
Number 4 Vol.2 (4), 1999 |
Number 4 Vol.1 (4), 1998 |
Number 4 3&4, 2001 |
Number 4 1&2, 2001 |
Number 3 Vol.3 (3), 2000 |
Number 3 Vol.2 (3), 1999 |
Number 3 Vol.1 (3), 1998 |
Number 2 Vol.3(2), 2000 |
Number 2 Vol.1 (2), 1998 |
Number 2 Vol.2 (2), 1999 |
Number 1 Vol.3 (1), 2000 |
Number 1 Vol.2 (1), 1999 |
Number 1 Vol.1 (1), 1998 |
|
|