MOLECULAR MONITORING OF CHIMERISM AFTER BONE MARROW TRANSPLANTATION IN BULGARIA
Velizarova M1, Zaharieva B2, Dimova I2, Nikolova D2, Atanasova S2, Avramova B3, Mihailov G3, Jordanova M3, Bobev D3, Toncheva D2,*
*Corresponding Author: Professor Draga Toncheva, Department of Medical Genetics, Medical Faculty of Sofia, 2 Zdrave str., 1431 Sofia, Bulgaria; Tel./Fax: +359-2-9520357; E-mail: dragatoncheva@yahoo.com
page: 37

REFERENCES

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5. Ugozzoli L, Yam P, Petz LD, Ferrara GB, Champlin RE, Forman SJ, Koyal D, Wallace RB. Amplification by the polymerase chain reaction of hypervariable regions of the human genome for evaluation of chimerism after bone marrow transplantation. Blood 1991; 77(3): 1607-1615.
6. Martinelli G, Trabetti E, Farabegoli P, Testoni N, Bandini G, Motta MR, Vittone A, Terragna C, Pignatti PF, Tura S. Early detection of bone marrow engraftment by amplification of hypervariable DNA regions. Haema­tologica 1997; 82(2): 156-160.
7. Gaiger A, Mannhalter C, Hinterberger W, Haas O, Marosi C, Kier P, Eichinger S, Funovic M, Lechner K. Detection of engraftment and mixed chimerism following bone marrow transplantation using PCR amplification of a highly variable region-variable number of tandem repeats (VNTR) in the von Willebrand factor gene. Ann Hematol 1991; 63(4): 227-228.
8. Stuppia L, Calabrese G, Di Bartolomeo P, Peila R, Franchi PG, Morizio E, Palka G. Retrospective investigation of hematopoietic chimerism after BMT by PCR amplification of hypervariable DNA regions. Cancer Genet Cytogenet 1995; 85(2): 124-128.
9. Jolkowska J, Wachowiak J, Lange A, Kwissa M, Witt M. Molecular assessment of post-BMT chimerism using various biologic specimens and automated DNA sizing technology. J Hematother Stem Cell Res 2000; 9(2): 263-268.
10. Winiarski J, Gustafsson A, Wester D, Dalianis T. Follow-up of chimerism, including T- and B-lymphocytes and granulocytes in children more than one year after allogeneic bone marrow transplantation. Pediatr Transplant 2000; 4(2): 132-139.
11. Fundia AF, De Brasi C, Larripa I. Feasibility of a cost-effective approach to evaluate short tandem repeat markers suitable for chimerism follow-up. Mol Diagn 2004; 8(2): 87-91.
12. Grubic Z, Stingl K, Cecuk-Jelicic E, Zunec R, Serventi Seiwerth R, Labar B, Rajic Lj, Brkljacic-Kerhin V. Evaluation of mixed chimerism in bone marrow transplantation program in Croatia. Transplant Proc 2005; 37(2): 1388-1391.
13. Grubic Z, Stingl K, Cecuk Jelicic E, Zunec R, Kastelan A, Serventi Seiwerth R, Bogdanic V, Labar B, Kerhin Brkljacic V. Repetitive DNA polymorphisms in following chimerism after allogeneic bone marrow transplantation. Clin Transplant 2005; 19(2): 586-590.
14. Buno I, Nava P, Simon A, Gonzalez-Rivera M, Jimenez JL, Balsalobre P, Serrano D, Carrion R, Gomez-Pineda A, Diez-Martin JL. A comparison of fluorescent in situ hybridization and multiplex short tandem repeat polymerase chain reaction for quantifying chimerism after stem cell transplantation. Haematologica 2005; 90(10): 1373-1379.
15. Lee KH, Lee JH, Choi SJ, Lee JH, Kim S, Seol M, Lee YS, Kim WK, Kwon MR, Choi SJ, Park CJ, Chi HS, Lee JS. Monthly prospective analysis of hemato­poietic chimerism after allogeneic hematopoietic cell transplantation. Bone Marrow Transplant 2003; 32(4): 423-431.
16. Bader P, Holle W, Klingebiel T, Handgretinger R, Benda N, Schlegel PG, Niethammer D, Beck J. Mixed hematopoietic chimerism after allogeneic bone marrow transplantation: the impact of quantitative PCR analysis for prediction of relapse and graft rejection in children. Bone Marrow Transplant 1997; 19(7): 697-702.




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