ANXA5 AND VEGFA GENE VARIANTS
IN WOMEN WITH EARLY PREGNANCY LOSSES
FROM NORTH MACEDONIA
Terzikj M, Bozhinovski Gj, Branoski A, Dimkovska M, Kubelka-Sabit K, Plaseska-Karanfilska D
*Corresponding Author: Corresponding author, Prof. Dijana Plaseska-Karanfilska, MD, PhD.
Research Centre for Genetic Engineering and Biotechnology “Georgi D. Efremov”,
Macedonian Academy of Science and Arts, Skopje, North Macedonia, e-mail: dijana@manu.edu.mk
page: 5
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CONCLUSION
Our current study introduces a cost-effective geno-
typing method for selected ANXA5 and VEGFA variants.
Additionally, our study is in line with numerous studies,
supporting the concept that M2 and M1 ANXA5 haplotypes
are more common in patients experiencing pregnancy loss.
Moreover, since there are data on some experimental thera-
pies for the individuals carrying primarily the M2/ANXA5
haplotype, a research in that direction and clinical studies
for therapy justification could be a further step.
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