IDENTIFICATION OF KEY TARGET GENES AND
PATHWAY ANALYSIS IN NONALCOHOLIC FATTY LIVER
DISEASE VIA INTEGRATED BIOINFORMATICS ANALYSIS
Chen X.1, Zhang L.2, Wang Y.1, Li R.1, Yang M.1, Gao L.3*
*Corresponding Author: Lei Gao, MD, College of Basic Medicine, Changchun University of Chinese
Medicine, 1035 Boshuo, Road, Jingyue District, Changchun City, Jilin Province, 130117, China;
Tel:+ 86-431-8604 5309, Email: gaolei790708@163.com
page: 10
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CONCLUSION
In conclusion, this study constructed and analyzed
a ceRNA network, a network which may provide some
evidence for future studies focusing on the molecular
mechanisms of NALFD. LEPR, CXCL10, and FOXO1
may function as ceRNAs to serve critical roles in NALFD.
In addition, antipsychotics, atorvastatin, valproic acid, risperidone,
clozapine, olanzapine, simvastatin, quetiapine,
peginterferon alfa-2a, peginterferon alfa-2b, epirubicin,
cyclophosphamide, and fluorouracil may produce therapeutic
effect for patients with NALFD.
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