ASSOCIATION OF GENETIC POLYMORPHISMS IN THE Matrix Gla Protein (MGP) GENE WITH CORONARY ARTERY DISEASE AND SERUM MGP LEVELS
Karsli-Ceppioglu S1,*, Yazar S2, Keskin Y3, Karaca M4, Luleci NE3, Yurdun T1
*Corresponding Author: Seher Karsli-Ceppioglu, Ph.D., Department of Toxicology, Faculty of Pharmacy, Marmara University, Tibbiye Street No. 49, İstanbul 34668, Turkey. Tel: +90-216-414-2962. Fax: +90-216-345-2952. E-mail: seher.karsli@marmara.edu.tr
page: 43

REFERENCES

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Assessment of matrix Gla protein, Klotho gene polymorphisms, and oxidative stress in chronic kidney disease. Ren Fail. 2011; 33(9): 866-874. 11. Garbuzova VY, Gurianova VL, Stroy DA, Dosenko VE, Parkhomenko AN, Ataman AV. Association of matrix Gla protein gene allelic polymorphisms (G(- 7)→A, T(-138)→C and Thr(83)→Ala) with acute coronary syndrome in the Ukrainian population. Exp Clin Cardiol. 2012; 17(1): 30-33. 12. Barrett JC, Fry B, Maller J, Daly MJ. Haploview: Analysis and visualization of LD and haplotype maps. Bioinformatics. 2005; 21(2): 263-265. 13. Cassidy-Bushrow AE, Bielak LF, Levin AM, Sheedy PF 2nd, Turner ST, Boerwinkle E, et al. Matrix gla protein gene polymorphism is associated with increased coronary artery calcification progression. Arterioscler Thromb Vasc Biol. 2013; 33(3): 645-651. 14. Najafi M, Roustazadeh A, Amirfarhangi A, Kazemi B. Matrix Gla protein (MGP) promoter polymorphic variants and its serum level in stenosis of coronary artery. Mol Biol Rep. 2014; 41(3): 1779-1786. 15. Kobayashi N, Kitazawa R, Maeda S, Schurgers L, Kitazawa S. T-138C polymorphism of matrix gla protein promoter alters its expression but is not directly associated with atherosclerotic vascular calcification. Kobe J Med Sci. 2004; 50(3-4): 69-81. 16. Crosier MD, Booth SL, Peter I, Dawson-Hughes B, Price PA, O’Donnell CJ, et al. Matrix Gla protein poly-morphisms are associated with coronary artery calcification in men. J Nutr Sci Vitaminol (Tokyo). 2009; 55(1): 59-65. 17. Brancaccio D, Biondi ML, Gallieni M, Turri O, Galassi A, Cecchini F, et al. Matrix GLA protein gene polymorphisms: Clinical correlates and cardiovascular mortality in chronic kidney disease patients. Am J Nephrol. 2005; 25(6): 548-552. 18. Sheng K, Zhang P, Lin W, Cheng J, Li J, Chen J. Association of Matrix Gla protein gene (rs1800801, rs1800802, rs4236) polymorphism with vascular calcification and atherosclerotic disease: A metaanalysis. Sci Rep. 2017; 7(1): 8713-8724. 19. Schurgers LJ, Teunissen KJ, Knapen MH, Kwaijtaal M, van Diest R, Appels A, et al. Novel con-formationspecific antibodies against matrix γ-carboxyglutamic acid (Gla) protein: Undercarboxylated matrix Gla protein as marker for vascular calcification. Arterioscler Thromb Vasc Biol. 2005; 25(8): 1629-1633. 20. Sweatt A, Sane DC, Hutson SM, Wallin R. Matrix Gla protein (MGP) and bone morphogenetic protein-2 in aortic calcified lesions of aging rats. J Thromb Haemost. 2003; 1(1): 178-185. 21. Roumeliotis S, Dounousi E, Eleftheriadis T, Liakopoulos V. Association of the inactive circulating matrix gla protein with vitamin K intake, calcification, mortality, and cardiovascular disease: A review. Int J Mol Sci. 2019; 20(3): 628-655. 22. Schurgers LJ, Barreto DV, Barreto FC, Liabeuf S, Renard C, Magdeleyns EJ, et al. The circulating inactive form of matrix gla protein is a surrogate marker for vascular calcification in chronic kidney disease: A preliminary report. 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