TWIST1 GENE EXPRESSION AS A BIOMARKER FOR PREDICTING PRIMARY DOXORUBICIN RESISTANCE IN BREAST CANCER
Demir S1,10,*, Müslümanoğlu MH2, Müslümanoğlu M3, Başaran S4, Çalay ZZ5, Aydıner A6, Vogt U7, Çakır T8, Kadıoğlu H9, Artan S1
*Corresponding Author: Selma Demir, Ph.D., Trakya University Faculty of Medicine, Department of Medical Genetics, 22030 Iskender, Edirne, Turkey. Tel: +90(284)2357642/2330. Fax: +90(284)2357652. E-mail: selmaulusal@trakya.edu.tr
page: 25

REFERENCES

1. World Health Organization (https://www.who.int/ cancer/prevention/diagnosis-screening/breast-cancer/ en/). 2. Filipova A, Seifrtova M, Mokry J, Dvorak J, Rezacova M, Filip S, et al. Breast cancer and cancer stem cells: A mini-review. Tumori. 2014; 100(4): 363-369. 3. Dörfel S, Steffens CC, Meyer D, Tesch H, Kruggel L, Frank M, et al. Adjuvant chemotherapeutic treatment of 1650 patients with early breast cancer in routine care in Germany: Data from the prospective TMK cohort study. Breast Cancer. 2018; 25(3): 275-283. 4. Ribeiro JT, Macedo LT, Curigliano G, Fumagalli L, Locatelli M, Dalton M, et al. Cytotoxic drugs for patients with breast cancer in the era of targeted treatment: Back to the future? Ann Oncol. 2012; 23(3): 547-555. 5. Duffy MJ, O’Donovan N, McDermott E, Crown J. Validated biomarkers: The key to precision treatment in patients with breast cancer. Breast. 2016; 29: 192- 201. 6. Online Mendelian Inheritance in Man, OMIM®. Mc- Kusick-Nathans Institute of Genetic Medicine, Johns Hopkins University, Baltimore, MD, USA (https:// omim. org/). 7. Pajer P, Pecenka V, Karafiát V, Králová J, Horejsí Z, Dvorák M. The twist gene is a common target of retroviral integration and transcriptional deregulation in experimental nephroblastoma. Oncogene. 2003; 22(5): 665-673. 8. Yin G, Chen R, Alvero AB, Fu HH, Holmberg J, Glackin C, et al. TWISTing stemness, inflammation and proliferation of epithelial ovarian cancer cells through MIR199A2/214. Oncogene. 2010; 29(24): 3545-353. 9. Tseng JC, Chen HF, Wu KJ. A twist tale of cancer metastasis and tumor angiogenesis. Histol Histopathol. 2015; 30(11): 1283-1294. 10. Norozi F, Ahmadzadeh A, Shahjahani M, Sharabi S, Saki N. Twist as a new prognostic marker in hematological malignancies. Clin Transl Oncol. 2016; 18(2): 113-124. 11. Zhao Z, Rahman MA, Chen ZG, Shin DM. Multiple biological functions of Twist1 in various cancers. Oncotarget. 2017; 8(12): 20380-20393. 12. Qiao W, Jia Z, Liu H, Liu Q, Zhang T, Guo W, et al. Prognostic and clinicopathological value of Twist expression in breast cancer: A meta-analysis. PLoS One. 2017; 12(10): e0186191-e0186202. 13. Andreotti PE, Linder D, Hartmann DM, Cree IA, Pazzagli M, Bruckner HW. TCA-100 tumour chemosensitivity assay: Differences in sensitivity between cultured tumour cell lines and clinical studies. J Biolumin Chemilumin. 1994; 9(6): 373-378. 14. Cree IA, Kurbacher CM, Untch M, Sutherland LA, Hunter EM, Subedi AM, et al. Correlation of the clinical response to chemotherapy in breast cancer with ex vivo chemosensitivity. Anticancer Drugs. 1996; 7(6): 630-635. 15. Vogt U, Bielawski KP, Bosse U, Schlotter CM. Breast tumour growth inhibition in vitro through the combination of cyclophosphamide/metotrexate/5- fluorouracil, epirubicin/cyclophosphamide, epirubicin/ paclitaxel, and epirubicin/docetaxel with the bisphosphonates ibandronate and zoledronic acid. Oncol Rep. 2004; 12(5): 1109-1114. 16. Kurbacher CM, Cree IA. Chemosensitivity testing using microplate adenosine triphosphate-based luminescence measurements. Methods Mol Med. 2005; 110: 101-120. 17. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001; 25(4): 402-408. 18. Zelnak A. Overcoming taxane and anthracycline resistance. Breast J. 2010; 16(3): 309-312. 19. Hofmann D, Nitz U, Gluz O, Kates RE, Schin-koethe T, Staib T, et al. WSG ADAPT – adjuvant dynamic marker-adjusted personalized therapy trial optimizing risk assessment and therapy response prediction in early breast cancer: Study protocol for a prospective, multi-center, controlled, non-blinded, randomized, investigator initiated phase II/III trial. Trials. 2013; 14: 261. doi: 10.1186/1745- 6215-14-261. 20. Ayyagari VN, Hsieh TJ, Diaz-Sylvester PL, Brard L. Evaluation of the cytotoxicity of the Bithionolcisplatin combination in a panel of human ovarian cancer cell lines. BMC Cancer. 2017; 17(1): 49. 21. Smith SC, Baras AS, Lee JK, Theodorescu D. The COXEN principle: Translating signatures of in vitro chemosensitivity into tools for clinical outcome prediction and drug discovery in cancer. Cancer Res. 2010; 70(5): 1753-1758. 22. Wang LF, Yin HT, Qian XP, Wei J, Zhao Y, Yu LX, et al. Beta-Tubulin III mRNA expression and docetaxel sensitivity in non-small cell lung cancer. Clin Invest Med. 2009; 32(6): E278-E284. 23. Maestro R, Dei Tos AP, Hamamori Y, Krasnokutsky S, Sartorelli V, Kedes L, et al. Twist is a potential oncogene that inhibits apoptosis. Genes Dev. 1999; 13(17): 2207-2217. 24. Pham CG, Bubici C, Zazzeroni F, Knabb JR, Papa S, Kuntzen C, et al. Upregulation of Twist-1 by NFkappaB blocks cytotoxicity induced by chemotherapeutic drugs. Mol Cell Biol. 2007; 27(11): 3920-3935. 25. Wang L, Tan RZ, Zhang ZX, Yin R, Zhang YL, Cui WJ, et al. Association between Twist and multidrug resistance gene-associated proteins in Taxol®-resistantMCF- 7 cells and a 293 cell model of Twist overexpression. Oncol Lett. 2018; 15(1): 1058-1066. 26. Li QQ, Xu JD, Wang WJ, Cao XX, Chen Q, Tang F, et al. Twist1-mediated adriamycin-induced epithelialmesenchymal transition relates to multidrug resistance and invasive potential in breast cancer cells. Clin Cancer Res. 2009; 15(8): 2657-2665. 27. Saxena M, Stephens MA, Pathak H, Rangarajan A. Transcription factors that mediate epithelial-mesenchymal transition lead to multidrug resistance by upregulating ABC transporters. Cell Death Dis. 2011; 2: e179-e191. 28. Hillen F, Griffioen AW. Tumour vascularization: Sprouting angiogenesis and beyond. Cancer Metastasis Rev. 2007; 26(3-4): 489-502 29. Flamant L, Roegiers E, Pierre M, Hayez A, Sterpin C, De Backer O, et al. TMEM45A is essential for hypoxia-induced chemoresistance in breast and liver cancer cells. BMC Cancer. 2012; 12: 391-407.



Number 27
VOL. 27 (2), 2024
Number 27
VOL. 27 (1), 2024
Number 26
Number 26 VOL. 26(2), 2023 All in one
Number 26
VOL. 26(2), 2023
Number 26
VOL. 26, 2023 Supplement
Number 26
VOL. 26(1), 2023
Number 25
VOL. 25(2), 2022
Number 25
VOL. 25 (1), 2022
Number 24
VOL. 24(2), 2021
Number 24
VOL. 24(1), 2021
Number 23
VOL. 23(2), 2020
Number 22
VOL. 22(2), 2019
Number 22
VOL. 22(1), 2019
Number 22
VOL. 22, 2019 Supplement
Number 21
VOL. 21(2), 2018
Number 21
VOL. 21 (1), 2018
Number 21
VOL. 21, 2018 Supplement
Number 20
VOL. 20 (2), 2017
Number 20
VOL. 20 (1), 2017
Number 19
VOL. 19 (2), 2016
Number 19
VOL. 19 (1), 2016
Number 18
VOL. 18 (2), 2015
Number 18
VOL. 18 (1), 2015
Number 17
VOL. 17 (2), 2014
Number 17
VOL. 17 (1), 2014
Number 16
VOL. 16 (2), 2013
Number 16
VOL. 16 (1), 2013
Number 15
VOL. 15 (2), 2012
Number 15
VOL. 15, 2012 Supplement
Number 15
Vol. 15 (1), 2012
Number 14
14 - Vol. 14 (2), 2011
Number 14
The 9th Balkan Congress of Medical Genetics
Number 14
14 - Vol. 14 (1), 2011
Number 13
Vol. 13 (2), 2010
Number 13
Vol.13 (1), 2010
Number 12
Vol.12 (2), 2009
Number 12
Vol.12 (1), 2009
Number 11
Vol.11 (2),2008
Number 11
Vol.11 (1),2008
Number 10
Vol.10 (2), 2007
Number 10
10 (1),2007
Number 9
1&2, 2006
Number 9
3&4, 2006
Number 8
1&2, 2005
Number 8
3&4, 2004
Number 7
1&2, 2004
Number 6
3&4, 2003
Number 6
1&2, 2003
Number 5
3&4, 2002
Number 5
1&2, 2002
Number 4
Vol.3 (4), 2000
Number 4
Vol.2 (4), 1999
Number 4
Vol.1 (4), 1998
Number 4
3&4, 2001
Number 4
1&2, 2001
Number 3
Vol.3 (3), 2000
Number 3
Vol.2 (3), 1999
Number 3
Vol.1 (3), 1998
Number 2
Vol.3(2), 2000
Number 2
Vol.1 (2), 1998
Number 2
Vol.2 (2), 1999
Number 1
Vol.3 (1), 2000
Number 1
Vol.2 (1), 1999
Number 1
Vol.1 (1), 1998

 

 


 About the journal ::: Editorial ::: Subscription ::: Information for authors ::: Contact
 Copyright © Balkan Journal of Medical Genetics 2006