RESULTS OF LIQUID BIOPSY STUDIES BY NEXT
GENERATION SEQUENCING IN PATIENTS WITH
ADVANCED STAGE NON-SMALL CELL LUNG CANCER:
SINGLE CENTER EXPERIENCE FROM TURKEY
Buyuksimsek M1,*, Togun M2, Oguz Kara I1, Bisgin A3,4, Boga I4, Tohumcuoglu M1,
Ogul A1, Evren Yetisir A1, Sahin B1, Erdem Sumbul H5, Mirili C6
*Corresponding Author: Mahmut Buyuksimsek, M.D., Department of Oncology, Çukurova University
Faculty of Medicine, Sarican, Adana, Turkey. Tel: +90-536-862-20-26. Fax: +90-322-338-70-72.
E-mail: mahmutbuyuksimsek@gmail.com
page: 17
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CONCLUSIONS
In the present study we reported the results of targeted
multigene panel NGS analysis of ccfDNA in Turkish patients
with NSCLC. We demonstrated the feasibility of this
advanced diagnostic method and identified mutations of
resistance and potential treatment target. We suggest that
the non invasive liquid biopsy will have a great clinical
importance in the management of patients with NSCLC
when obtained tissue samples are inadequate or repeat
biopsy is difficult.
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