GENETIC VARIATION OF THE BRCA1 AND BRCA2 GENES IN MACEDONIAN PATIENTS
Maleva I1, Madjunkova S1, Bozhinovski G1, Smickova E2, Kondov G3, Spiroski Z3, Arsovski A4, Plaseska-Karanfilska D1,*
*Corresponding Author: Professor Dr. Dijana Plaseska-Karanfilska, Research Centre for Genetic Engineering and Biotechnology “Georgi D. Efremov,” Macedonian Academy of Sciences and Arts, Krste Misirkov 2, Skopje 1000, Republic of Macedonia; Tel: +389(0)2 3235410; Fax: +389 (0)2 3115434; E-mail: dijana@manu.edu.mk
page: 81

REFERENCES

1. Miki Y, Swensen J, Shattuck-Eidens D, et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science. 1994; 266(5182): 66-71. 2. Wooster R, Bignell G, Lancaster J, et al. Identification of the breast cancer susceptibility gene BRCA2. Nature. 1995; 378(6559): 789-792. 3. Walsh T, King MC. Ten genes for inherited breast cancer. Cancer Cell. 2007; 11(2): 103-5. 4. Fackenthal JD, Olopade OI. Breast cancer risk associated with BRCA1 and BRCA2 in diverse populations. Nat Rev Cancer. 2007; 7(12): 937-948. 5. Ferla R, Calo V, Cascio S, et al. Founder mutations in BRCA1 and BRCA2 genes. Ann Oncol. 2007; 18 (Suppl 6): vi93-98. 6. Balmana J, Diez O, Castiglione M. BRCA in breast cancer: ESMO clinical recommendations. Ann Oncol. 2009; 20(Suppl 4): 19-20. 7. De Greve J, Sermijn E, De Brakeleer S, Ren Z, Teugels E. Hereditary breast cancer: from bench to bedside. Curr Opin Oncol. 2008; 20(6): 605-613. 8. Rouleau M, Patel A, Hendzel MJ, Kaufmann SH, Poirier GG. PARP inhibition: PARP1 and beyond. Nat Rev Cancer. 2010; 10(4): 293-301. 9. Byrski T, Gronwald J, Huzarski T, et al. Pathologic complete response rates in young women with BRCA1-positive breast cancers after neoadjuvant chemotherapy. J Clin Oncol. 2010; 28(3): 375-379. 10. Neuhausen SL. Founder populations and their uses for breast cancer genetics. Breast Cancer Res. 2000; 2(2): 77-81. 11. Freedman ML, Penney KL, Stram DO, et al. A haplotype- based case-control study of BRCA1 and sporadic breast cancer risk. Cancer Res. 2005; 65(16): 7516-7522. 12. Ewald IP, Ribeiro PL, Palmero EI, Cossio SL, Giugliani R, Ashton-Prolla P. Genomic rearrangements in BRCA1 and BRCA2: A literature review. Genet Mol Biol. 2009; 32(3): 437-446. 13. Cox DG, Kraft P, Hankinson SE, Hunter DJ. Haplotype analysis of common variants in the BRCA1 gene and risk of sporadic breast cancer. Breast Cancer Res. 2005; 7(2): R171-R175. 14. Qiu LX, Yao L, Xue K, et al. BRCA2 N372H polymorphism and breast cancer susceptibility: a metaanalysis involving 44,903 subjects. Breast Cancer Res Treat. 2010; 123(2): 487-490.



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