CAG REPEAT NUMBER IN THE ANDROGEN RECEPTOR GENE AND PROSTATE CANCER
Madjunkova S, Eftimov A, Georgiev V, Petrovski D, Dimovski AJ, Plaseska- Karanfi lska D,
*Corresponding Author: Professor Dr. Dijana Plaseska-Karanfi lska, Macedonian Academy of Sciences and Arts, Research Center for Genetic Engineering and Biotechnology “Georgi D. Efremov”, Av. Krste Misirkov 2, POB 428, 1000 Skopje, Republic of Macedonia; Tel.: +389-2-3235-410; Fax: +389-2-3115- 434; E-mail: dijana@manu.edu.mk
page: 31

REFERENCES

1. Crawford ED. Epidemiology of prostate cancer. Urology. 2003; 62(6): 3-12. 2. Gronberg H. Prostate cancer epidemiology. Lancet. 2003; 361(9360): 859-864. 3. Haas GP, Sakr WA. Epidemiology of prostate cancer. CA Cancer J Clin. 1997; 47(5): 273-287. 4. Scosyrev E, Messing EM, Mohile S, Golijanin D, Wu G. Prostate cancer in the elderly: frequency of advanced disease at presentation and disease-specific mortality. Cancer. 2011; doi: 10.1002/cncr.26392. [Epub ahead of print]. 5. Nelson KA, Witte JS. Androgen receptor CAG repeats and prostate cancer. Am J Epidemiol. 2002; 155(10): 883-890. 6. Mittal RD, Mishra D, Mandhani AK. Role of an an drogen receptor gene polymorphism in development of hormone refractory prostate cancer in Indian population. Asian Pac J Cancer Prev. 2007; 8(2): 275-278. 7. Cotter MP, Gern RW, Ho GY, Chang RY, Burk RD. Role of family history and ethnicity on the mode and age of prostate cancer presentation. Prostate. 2002; 50(4): 216-221. 8. Du XL, Fang S, Coker AL, Sanderson M, Aragaki C, Cormier JN, Xing Y, Gor BJ, Chan W. Racial disparity and socioeconomic status in association with survival in older men with local/regional stage prostate carcinoma: fi ndings from a large communitybased cohort. Cancer. 2006; 106(6): 1276-1285. 9. Schaid DJ. The complex genetic epidemiology of prostate cancer. Hum Mol Genet. 2004; 13(Spec No 1): R103-121. 10. Feldman BJ, Feldman D. The development of andro gen-independent prostate cancer. Nat Rev Cancer. 2001; 1(1): 34-45. 11. Lu S, Tsai SY, Tsai MJ. Regulation of androgendependent prostatic cancer cell growth: androgen regulation of CDK2, CDK4, and CKI p16 genes. Cancer Res. 1997; 57(20): 4511-4516. 12. Montgomery JS, Price DK, Figg WD. The androgen receptor gene and its infl uence on the development and progression of prostate cancer. J Pathol. 2001; 195(2): 138-146. 13. Edwards A, Hammond HA, Jin L, Caskey CT, Chakraborty R. Genetic variation at fi ve trimeric and tetrameric tandem repeat loci in four human population groups. Genomics. 1992; 12(2): 241-253. 14. Giovannucci E, Stampfer MJ, Krithivas K, Brown M, Dahl D, Brufsky A, Talcott J, Hennekens CH, Kantoff PW. The CAG repeat within the androgen receptor gene and its relationship to prostate cancer. Proc Natl Acad Sci USA. 1997; 94(7): 3320-3323. 15. Chamberlain NL, Driver ED, Miesfeld RL. The length and location of CAG trinucleotide repeats in the androgen receptor N-terminal domain affect transactivation function. Nucleic Acids Res .1994; 22(15): 3181-3186. 16. Hardy DO, Scher HI, Bogenreider T, Sabbatini P, Zhang ZF, Nanus DM, Catterall JF. Androgen receptor CAG repeat lengths in prostate cancer: correlation with age of onset. J Clin Endocrinol Metab. 1996; 81(12): 4400-4405. 17. Stanford JL, Just JJ, Gibbs M, Wicklund KG, Neal CL, Blumenstein BA, Ostrander EA. Polymorphic repeats in the androgen receptor gene: molecular markers of prostate cancer risk. Cancer Res. 1997; 57(6): 1194-1198. 18. Irvine RA, Yu MC, Ross RK, Coetzee GA. The CAG and GGC microsatellites of the androgen receptor gene are in linkage disequilibrium in men with prostate cancer. Cancer Res. 1995; 55(9): 1937-1940. 19. Zeegers MP, Kiemeney LA, Nieder AM, Ostrer H. How strong is the association between CAG and GGN repeat length polymorphisms in the androgen receptor gene and prostate cancer risk? Cancer Epidemiol Biomarkers Prev. 2004; 13(11): 1765-1771. 20. Price DK, Chau CH, Till C, Goodman PJ, Baum CE, Ockers SB, English BC, Minasian L, Parnes HL, Hsing AW, Reichardt JK, Hoque A, Tangen CM, Kristal AR, Thompson IM, Figg WD. Androgen receptor CAG repeat length and association with prostate cancer risk: results from the prostate cancer prevention trial. J Urol. 2010; 184(6): 2297-2302. 21. Lindstrom S, Ma J, Altshuler D, Giovannucci E, Riboli E, Albanes D, Allen NE, Berndt SI, Boeing H, Bueno-de-Mesquita HB, Chanock SJ, Dunning AM, Feigelson HS, Gaziano JM, Haiman CA, Hayes RB, Henderson BE, Hunter DJ, Kaaks R, Kolonel LN, Le Marchand L, Martinez C, Overvad K, Siddiq A, Stampfer M, Stattin P, Stram DO, Thun MJ, Trichopoulos D, Tumino R, Virtamo J, Weinstein SJ, Yeager M, Kraft P, Freedman ML. A large study of androgen receptor germline variants and their relation to sex hormone levels and prostate cancer risk. Results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium. J Clin Endocrinol Metab. 2010; 95(9): E121-E127. 22. Mishra D, Thangaraj K, Mandhani A, Kumar A, Mittal R. Is reduced CAG repeat length in androgen receptor gene associated with risk of prostate cancer in Indian population? Clin Genet. 2005; 68(1): 55-60. 23. Hakimi JM, Schoenberg MP, Rondinelli RH, Piantadosi S, Barrack ER. Androgen receptor variants with short glutamine or glycine repeats may identify unique subpopulations of men with prostate cancer. Clin Cancer Res. 1997; 3(9): 1599-1608. 24. Hsing AW, Gao YT, Wu G, Wang X, Deng J, Chen YL, Sesterhenn IA, Mostofi FK, Benichou J, Chang C. Polymorphic CAG and GGN repeat lengths in the androgen receptor gene and prostate cancer risk: a population-based case-control study in China. Cancer Res. 2000; 60(18): 5111-5116. 25. Akinloye O, Gromoll J, Simoni M. Variation in CAG and GGN repeat lengths and CAG/GGN haplotype in androgen receptor gene polymorphism and prostate carcinoma in Nigerians. Br J Biomed Sci. 2011; 68(3): 138-142. 26. Plaseski T, Noveski P, Dimitrovski C, Kocevska B, Efremov GD, Plaseska-Karanfi lska D. CAG Repeat number in androgen receptor gene and male infertility. BJMG. 2007; 10(1): 19-24. 27. Coetzee GA, Ross RK. Re: prostate cancer and the androgen receptor. J Natl Cancer Inst. 1994; 86(11): 872-873. 28. Ding D, Xu L, Menon M, Reddy GP, Barrack ER. Effect of a short CAG (glutamine) repeat on human androgen receptor function. Prostate. 2004; 58(1): 23-32. 29. Gu M, Dong X, Zhang X, Niu W. The CAG repeat polymorphism of androgen receptor gene and prostate cancer: a meta-analysis. Mol Biol Rep. 2011; 39(3): 2615-2624. 30. Binnie MC, Alexander FE, Heald C, Habib FK. Polymorphic forms of prostate specifi c antigen and their interaction with androgen receptor trinucleotide repeats in prostate cancer. Prostate. 2005; 63(4): 309-315. 31. Correa-Cerro L, Wohr G, Haussler J, Berthon P, Drelon E, Mangin P, Fournier G, Cussenot O, Kraus P, Just W, Paiss T, Cantu JM, Vogel W. (CAG)nCAA and GGN repeats in the human androgen receptor gene are not associated with prostate cancer in a French-German population. Eur J Hum Genet. 1999; 7(3): 357-362. 32. Salinas CA, Austin MA, Ostrander EO, Stanford JL. Polymorphisms in the androgen receptor and the prostate-specifi c antigen genes and prostate cancer risk. Prostate. 2005; 65(1): 58-65. 33. Jemal A, Siegel R, Xu J, Ward E. Cancer statistics, 2010. CA Cancer J Clin. 2010; 60(5): 277-300. 34. Polednak AP. Trends in prostate carcinoma inci dence in Connecticut (1988-1994) by age and race. Cancer. 1997; 79(1): 99-103. 35. Rodriguez-Gonzalez G, Cabrera S, Ramirez- Moreno R, Bilbao C, Diaz-Chico JC, Serra L, Chesa N, Cabrera JJ, Diaz-Chico BN. Short alleles of both GGN and CAG repeats at the exon-1 of the androgen receptor gene are associated to increased PSA staining and a higher Gleason score in human prostatic cancer. J Steroid Biochem Mol Biol. 2009; 113(1-2): 85-91. 36. Platz EA, Giovannucci E, Dahl DM, Krithivas K, Hennekens CH, Brown M, Stampfer MJ, Kantoff PW. The androgen receptor gene GGN microsatellite and prostate cancer risk. Cancer Epidemiol Biomarkers Prev. 1998; 7(5): 379-384. 37. Platz EA, Leitzmann MF, Rifai N, Kantoff PW, Chen YC, Stampfer MJ, Willett WC, Giovannucci E. Sex steroid hormones and the androgen receptor gene CAG repeat and subsequent risk of prostate cancer in the prostate-specifi c antigen era. Cancer Epidemiol Biomarkers Prev. 2005; 14(5): 1262-1269. 38. Bousema JT, Bussemakers MJ, van Houwelingen KP, Debruyne FM, Verbeek AL, de La Rosette JJ, Kiemeney LA. Polymorphisms in the vitamin D receptor gene and the androgen receptor gene and the risk of benign prostatic hyperplasia. Eur Urol. 2000; 37(2): 234-238. 39. Kristal AR, Price DK, Till C, Schenk JM, Neuhouser ML, Ockers S, Lin DW, Thompson IM, Figg WD. Androgen receptor CAG repeat length is not associated with the risk of incident symptomatic benign prostatic hyperplasia: results from the Prostate Cancer Prevention Trial. Prostate. 2010; 70(6): 584-590. 40. Gsur A, Preyer M, Haidinger G, Zidek T, Madersbacher S, Schatzl G, Marberger M, Vutuc C, Micksche M. Polymorphic CAG repeats in the androgen receptor gene, prostate-specifi c antigen polymorphism and prostate cancer risk. Carcinogenesis. 2002; 23(10): 1647-1651.



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