POLYMORPHISM OF THE IL13 GENE MAY BE ASSOCIATED WITH UTERINE LEIOMYOMAS IN SLOVENIAN WOMEN
Krsteski J, Jurgec S, Pakiž M, But I, Potočnik U,
*Corresponding Author: Professor Uroš Potočnik, Ph.D., Centre for Human Molecular Genetics and Pharmacogenomics, Faculty of Medicine, University of Maribor, Taborska Ulica 8, 2000 Maribor, Slovenia. Tel: +386-2-2345-854, Fax: +386-2- 2345-820, E-mail: uros.potocnik@um.si
page: 51

REFERENCES

1. Wallach EE, Vlahos NF. Uterine myomas: An overview of development, clinical features, and management. Obstet Gynecol. 2004; 104(2): 393-406. 2. Cramer SF, Patel A. The frequency of uterine leiomyomas. Am J Clin Pathol. 1990; 94(4): 435-438. 3. Marsh EE, Bulun SE. Steroid hormones and leio-myomas. Obstet Gynecol Clin North Am. 2006; 33(1): 59-67. 4. Walker CL, Stewart EA. Uterine fibroids: The elephant in the room. Science. 2005; 308(5728): 1589-1592. 5. Sandberg AA. Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: Leiomyoma. Cancer Genet Cytogenet. 2005; 158(1): 1-26. 6. Flake GP, Andersen J, Dixon D. Etiology and pathogenesis of uterine leiomyomas: A review. Environ Health Perspect. 2003; 111(8): 1037-1054. 7. Paltridge JL, Belle L, Khew-Goodall Y. The secretome in cancer progression. Biochim Biophys Acta. 2013; 1834(11): 2233-2241. 8. Li S, Jin T, Zhang J, Lou H, Yang B, Li Y, et al. Polymorphisms of TREH, IL4R and CCDC26 genes associated with risk of glioma. Cancer Epidemiol. 2012; 36(3): 283-287. 9. Yuan LJ, Jin TB, Yin JK, Du XL, Wang Q, Dong R, et al. Polymorphisms of tumor-related genes IL-10, PSCA, MTRR and NOC3L are associated with the risk of gastric cancer in the Chinese Han population. Cancer Epidemiol. 2012; 36(6): e366-e372. 10. Islam MS, Protic O, Stortoni P, Grechi G, Lamanna P, Petraglia F, et al. Complex networks of multiple factors in the pathogenesis of uterine leiomyoma. Fertil Steril. 2013; 100(1): 178-193. 11. Malyshkina AI, Posiseeva LV, Sotnikova NY, Antsiferova JS, Suvorkina EE, Arevadze IE. Local immunological markers of different rate of growth of uterine myoma. Russ J Immunol. 2002; 7(1): 58-62. 12. Sano M, Inoue S, Hosoi T, Ouchi Y, Emi M, Shiraki M, et al. Association of estrogen receptor dinucleotide repeat polymorphism with osteoporosis. Biochem Biophys Res Commun. 1995; 217(1): 378-383. 13. Hsieh YY, Chang CC, Tsai CH, Lin CC, Tsai FJ. Interleukin (IL)-12 receptor β1 codon 378 G homozygote and allele, but not IL-1 (β511 promoter, 3953 exon 5, receptor antagonist), IL-2 114, IL-4-590 intron 3, IL-8 3’-UTR 2767, and IL-18 105, are associated with higher susceptibility to leiomyoma. Fertil Steril. 2007; 87(4): 886-895. 14. Sosna O, Kolesár L, Slavčev A, Skibová J, Fait T, Mara M, et al. Th1/Th2 cytokine gene polymorphisms in patients with uterine fibroid. Folia Biol (Praha). 2010; 56(5): 206-210. 15. Pietrowski D, Thewes R, Sator M, Denschlag D, Keck C, Tempfer C. Uterine leiomyoma is associated with a polymorphism in the interleukin 1-β gene. Am J Reprod Immunol. 2009; 62(2): 112-127. 16. Taghizade-Mortezaee F, Hashemzadeh-Chaleshtori M, Kheiri S, Parvin N, Norbakhsh M, Etemadi S, et al. Association of interleukin-1β (IL-1β) gene polymorphisms with uterine leiomyoma. Zahedan J Res Med Sci. 2012; 14(7): 53-56. 17. Pakiz M, Potocnik U, But I. Solitary and multiple uterine leiomyomas among Caucasian women: Two different disorders? Fertil Steril. 2010; 94(6): 2291-2295. 18. Shao R, Fang L, Xing R, Xiong Y, Wang Z. Differential expression of estrogen receptor α and β isoforms in multiple and solitary leiomyomas. Biochem Biophys Res Commun. 2015; 468(1-2): 136-142. 19. Burkholder B, Huang RY, Burgess R, Luo S, Jones VS, Zhang W, et al. Tumor-induced perturbations of cytokines and immune cell networks. Biochim Biophys Acta. 2014; 1845(2): 182-201. 20. Cabantous S, Ranque S, Poudiougou B, Traore A, Berbache S, Vitte J, et al. Genotype combinations of two IL4 polymorphisms influencing IL-4 plasma levels are associated with different risks of severe malaria in the Malian population. Immunogenetics. 2015; 67(5-6): 283-288. 21. Mitsuyasu H, Izuhara K, Mao XQ, Gao PS, Arinobu Y, Enomoto T, et al. Ile50Val variant of IL4R α upregulates IgE synthesis and associates with atopic asthma. Nat Genet. 1998; 19(2): 119-120. 22. Xiao JP, Wang XR, Zhang S, Wang HY, Ye L, Pan HF, et al. Association between rs6887695 and 3’-untranslated region polymorphisms within the interleukin- 12B gene and susceptibility to autoimmune diseases in Asian and European population: A meta-analysis. Autoimmunity. 2016; 49(4): 277-284. 23. Jin T, Li X, Zhang J, Wang H, Geng T, Li G, et al. Genetic association between selected cytokine genes and glioblastoma in the Han Chinese population. BMC Cancer. 2013; 13: 236. 24. Hussain SK, Madeleine MM, Johnson LG, Du Q, Galloway DA, Daling JR, et al. Nucleotide variation in IL-10 and IL-12 and their receptors and cervical and vulvar cancer risk: A hybrid case-parent triad and case-control study. Int J Cancer. 2013; 133(1): 201-213. 25. Perneger TV. What’s wrong with Bonferroni adjustments. BMJ. 1998;316(7139):1236-1238. 26. Chu H, Wang M, Yan F, Zhong D, Shi D, Ma L, et al. Polymorphisms in the IL-13 and IL-4R genes are associated with the development of renal cell carcinoma. Ann Oncol. 2012; 23(8): 2114-2121. 27. Chu H, Ma L, Wang M, Shi D, Qin C, Yuan L, et al. The polymorphisms of IL-4, IL-4R and IL-13 genes and bladder cancer risk in a Chinese population: A casecontrol study. Mol Biol Rep. 2012; 39(5): 5349-5357. 28. Graves PE, Kabesch M, Halonen M, Holberg CJ, Baldini M, Fritzsch C, et al. A cluster of seven tightly linked polymorphisms in the IL-13 gene is associated with total serum IgE levels in three populations of white children. J Allergy Clin Immunol. 2000; 105(3): 506-513. 29. Schoemaker MJ, Swerdlow AJ, Hepworth SJ, van Tongeren M, Muir KR, McKinney PA. History of allergic disease and risk of meningioma. Am J Epidemiol. 2007; 165(5): 477-485. 30. Biggar RJ, Christiansen M, Rostgaard K, Smedby KE, Adami HO, Glimelius B, et al. Immunoglobulin subclass levels in patients with non-Hodgkin lymphoma. Int J Cancer. 2009; 124(11): 2616-2620. 31. van Toorenenbergen AW, van Heerde MJ, van Buuren HR. Potential value of serum total IgE for differentiation between autoimmune pancreatitis and pancreatic cancer. Scand J Immunol. 2010; 72(5): 444-448. 32. van der Pouw Kraan TC, van der Zee JS, Boeije LC, de Groot ER, Stapel SO, Aarden LA. The role of IL- 13 in IgE synthesis by allergic asthma patients. Clin Exp Immunol. 1998; 111(1): 129-135. 33. Luo X, Ding L, Xu J, Chegini N. Gene expression profiling of leiomyoma and myometrial smooth muscle cells in response to transforming growth factor-β. Endocrinology. 2005; 146(3): 1097-1118. 34. Kurachi O, Matsuo H, Samoto T, Maruo T. Tumor necrosis factor-α expression in human uterine leiomyoma and its down-regulation by progesterone. J Clin Endocrinol Metab. 2001; 86(5): 2275-2280. 35. McCawley LJ, Matrisian LM. Matrix metalloproteinases: They’re not just for matrix anymore! Curr Opin Cell Biol. 2001; 13(5): 534-540. 36. Wynn TA. IL-13 effector functions. Annu Rev Immunol. 2003; 21: 425-456. 37. Terabe M, Matsui S, Noben-Trauth N, Chen H, Watson C, Donaldson DD, et al. NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway. Nat Immunol. 2000; 1(6): 515-520. 38. Berzofsky JA, Terabe M. A novel immunoregulatory axis of NKT cell subsets regulating tumor immunity. Cancer Immunol Immunother. 2008; 57(11): 1679- 1683. 39. Zimmermann A, Bernuit D, Gerlinger C, Schaefers M, Geppert K. Prevalence, symptoms and management of uterine fibroids: An international internetbased survey of 21,746 women. BMC Womens Health. 2012; 12): 6. 40. Kobayashi M, Kobayashi H, Pollard RB, Suzuki F. A pathogenic role of Th2 cells and their cytokine products on the pulmonary metastasis of murine B16 melanoma. J Immunol. 1998; 160(12): 5869-5873. 41. Day FR, Helgason H, Chasman DI, Rose LM, Loh PR, Scott RA, et al. Physical and neurobehavioral determinants of reproductive onset and success. Nat Genet. 2016; 48(6): 617-623. 42. Pandis N, Karaiskos C, Bardi G, Sfikas K, Tserkezoglou A, Fotiou S, et al. Chromosome analysis of uterine adenomyosis. Detection of the leiomyomaassociated del(7q) in three cases. Cancer Genet Cytogenet. 1995; 80(2): 118-120. 43. van Voorhis BJ, Romitti PA, Jones MP. Family history as a risk factor for development of uterine leiomyomas. Results of a pilot study. J Reprod Med. 2002; 47(8): 663-669. 44. Marshall LM, Spiegelman D, Goldman MB, Manson JE, Colditz GA, Barbieri RL, et al. A prospective study of reproductive factors and oral contraceptive use in relation to the risk of uterine leiomyomata. Fertil Steril. 1998; 70(3): 432-439. 45. Moravek MB, Bulun SE. Endocrinology of uterine fibroids: Steroid hormones, stem cells, and genetic contribution. Curr Opin Obstet Gynecol. 2015; 27(4): 276-283.



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