Balkan Journal of Medical Genetics

THE GENETIC BACKGROUND OF SOUTHERN IRANIAN COUPLES BEFORE MARRIAGE
Nariman A, Sobhan MR, Savaei M, Aref-Eshghi E, Nourinejad R, Manoochehri M, Ghahremani S, Daliri F, Daliri K,*
*Corresponding Author: Dr. Karim Daliri, Department of Human Genetics, Behbahan Faculty of Medical Sciences, Bashir Boulevard, Behbahan, Iran. Tel: +98-9374140937. Fax: +98-9374140937. E-mail: karimdaliri@ gmail.com
page: 71

MATERIALS AND METHODS

Data Collection. The main proposal was approved by the Research Ethics Committee of Behbahan School of Paramedicine. All participants were assured that they had the right to refuse to sign the consent form. For the pilot study, 500 participants were selected from couples who were referred to the Behbahan Marital Counseling Center, located in Behbahan, a city in southern Iran, during the period from January to November 2014, to obtain information on consanguinity, disease history, and previous referral to a medical genetics center. The genetic counseling questionnaire included demographic data (age, sex and ethnicity), and information used to record different aspects of their medical history. Regarding genetic counseling services, we asked participants: “Have you ever been referred for genetic counseling before?” For those who answered yes, we asked them to provide the reason(s) for the referral(s) in a free-text item. We also asked participants: “Have you ever been referred for genetic testing, and if so, what were the results of the tests?” Other items evaluated their genetic background. One item asked respondents to specify whether their marriage was consanguineous (inbred) or non-consanguineous (outbred). Couples who were consanguineous were asked to indicate the degree of consanguinity. In a second item, the participants were asked to report any genetic diseases in their siblings or any experiences with infertility. Data Analysis. Descriptive statistics and classical tests of hypotheses were conducted using STATA 11.0 software (http://en.softonic.com/s/ spss-11.0-free-full-version?ex-TOP-207.3).

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