PRELIMINARY FINDINGS OF α-ACTININ-3 GENE DISTRIBUTION IN ELITE TURKISH WIND SURFERS
Ulucan K1, Göle S1, Altindas N2, Güney AI3
*Corresponding Author: Dr. Korkut Ulucan, Department of Molecular Biology and Genetics, Faculty of Engineering and Natural Sciences, Üsküdar University, Altunizade Mahallesi, Haluk Turksoy Sok., No. 14 Uskudar, Istanbul 34662, Turkey; +90-216-400-2222-2409, +90-216-474-1256; korkutulucan@hotmail.com
page: 69
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Abstract

A common polymorphism in the α-actinin-3 (ACTN3 R577X) gene represents one of the most widely examined variations in terms of performance and genetic predisposition to certain sports. The aim of the present study was to examine the ACTN3 R577X polymorphism in elite Turkish wind surfers. The genotyping procedure was carried out by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Five male and three female wind surfers, eight elite wind surfers in total, were enrolled in the study. Five of the surfers had RX, two had XX and one had RR genotypes. Previous findings indicated that the X allele was the endurance allele. Our findings were in agreement with the previous reports. Seven of our subjects had at least one copy of the X allele that was considered to have a tendency to prolong endurance. Our preliminary results must be supported with further studies in greater numbers of subjects to clarify the effect of gene polymorphism.



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