PP161. PRENATAL KARYOTYPES OF FETUSES CONCEIVED BY ASSISTED REPRODUCTIVE TREATMENT
A.-M. STEFANOVSKA, A. Anevska, M. Popovic, M. Ivanovski, S. Adamoska-Klisaroska, M. Vasilevska, S. Lazarevski Special hospital for obstetrics and gynecology - “Mala Bogorodica-Sistina”, Skopje, Republic of Macedonia e-mail: kliment@mt.net.mk
*Corresponding Author:
page: 120

Abstract

This study was designed as retrospective evaluation of prenatal karyotypes in fetuses conceived by assisted reproductive treatment (ART) in our hospital. During a 4-year period a total of 1466 ART cycles were recorded, performed by standard in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) method, including TESE (testicular sperm extraction). Of the 1157 embryo transfers that were carried out, pregnancies were confirmed in 297 patients and 265 babies were born. Chorion villus sampling or amniocentesis and prenatal karyotyping were performed in 57 fetuses from 52 (18%) patients considered at high risk due to advanced maternal age and ultrasound anomalies. Abnormal karyotypes were detected in 6 fetuses, three of these from singleton and three from twin pregnancies. Cytogenetic analysis revealed the common aneuploidies: three cases with trisomy 21, and one case each with trisomy 18, trisomy 13, and double trisomy 18 and X. Advanced maternal age was indication for prenatal diagnosis in all cases, except for trisomy 13 found in a 33 years old patient in whom ultrasound anomaly was detected. Three of the fetuses with chromosomal abnormalities were conceived by IVF, 2 by ICSI and one was obtained after embryo transfer of IVF and ICSI embryos. Our findings on prenatal karyotypes of ART fetuses are in agreement with previously reported data, especially from limited groups of high-risk patients similar to our group. Compared to the general population, ART conceived babies carry increased risk of an abnormal karyotype.




Number 20
VOL. 20 (1), 2017
Number 19
VOL. 19 (2), 2016
Number 19
VOL. 19 (1), 2016
Number 18
VOL. 18 (2), 2015
Number 18
VOL. 18 (1), 2015
Number 17
VOL. 17 (2), 2014
Number 17
VOL. 17 (1), 2014
Number 16
VOL. 16 (2), 2013
Number 16
VOL. 16 (1), 2013
Number 15
VOL. 15 (2), 2012
Number 15
VOL. 15, 2012 Supplement
Number 15
Vol. 15 (1), 2012
Number 14
14 - Vol. 14 (2), 2011
Number 14
The 9th Balkan Congress of Medical Genetics
Number 14
14 - Vol. 14 (1), 2011
Number 13
Vol. 13 (2), 2010
Number 13
Vol.13 (1), 2010
Number 12
Vol.12 (2), 2009
Number 12
Vol.12 (1), 2009
Number 11
Vol.11 (2),2008
Number 11
Vol.11 (1),2008
Number 10
Vol.10 (2), 2007
Number 10
10 (1),2007
Number 9
1&2, 2006
Number 9
3&4, 2006
Number 8
1&2, 2005
Number 8
3&4, 2004
Number 7
1&2, 2004
Number 6
3&4, 2003
Number 6
1&2, 2003
Number 5
3&4, 2002
Number 5
1&2, 2002
Number 4
Vol.3 (4), 2000
Number 4
Vol.2 (4), 1999
Number 4
Vol.1 (4), 1998
Number 4
3&4, 2001
Number 4
1&2, 2001
Number 3
Vol.3 (3), 2000
Number 3
Vol.2 (3), 1999
Number 3
Vol.1 (3), 1998
Number 2
Vol.3(2), 2000
Number 2
Vol.1 (2), 1998
Number 2
Vol.2 (2), 1999
Number 1
Vol.3 (1), 2000
Number 1
Vol.2 (1), 1999
Number 1
Vol.1 (1), 1998

 

 


 About the journal ::: Editorial ::: Subscription ::: Information for authors ::: Contact
 Copyright © Balkan Journal of Medical Genetics 2006