PP144. POLYMORPHISM OF ERYTHROCYTE GLYOXALASE (GLO-I E.C.4.4.1.5) IN THE BULGARIAN POPULATION FROM SOUTH-CENTRAL AND SOUTH-EASTERN REGION IN BULGARIA
S. BALTOVA & I. Popova Dept. of Anatomy and Physiology, Biological Faculty, University of Plovdiv, Bulgaria e-mail: bsofi@abv.bg
*Corresponding Author:
page: 112

Abstract

This paper consists of a study of the distribution of the erythrocyte glyoxalase (GLO-I E.C.4.4.1.5) within the population of the Bulgaria. Blood samples of 2559 clinically healthy subjects (males and females) of Bulgarian origin from south-central and south-eastern region of Bulgaria aged from 18 to 45 years were used in the study. The phenotype of GLO-I were done by the conventional methods. All established tests are only classical types of GLO-I. The distribution of phenotype was the following: 1-1- 14,03% individuals; 2-1 - 49,79% and 2-2 - 36,18%. The obtained allelic frequencies are those indicated fortwith: GLO-I 1 = 0,3892 and GLO-I 2 = 0,6108. The differences between the observed and theoretically expected values, evaluated with x-criterion, are insignificant (P>0,05) and resulting phenotype distribution adheres closely to Pearson law. The concordance between the observed and expected values is good and by Hardy-Weinberg law indicates that the studied population is in a state of genetic equilibrium with respect to the studied system. The results from the present investigation were compared with results in literature about other populations and it was found out that the Bulgarian population is part of the larger group of European people in terms of the studied factors.

 




Number 19
VOL. 19 (2), 2016
Number 19
VOL. 19 (1), 2016
Number 18
VOL. 18 (2), 2015
Number 18
VOL. 18 (1), 2015
Number 17
VOL. 17 (2), 2014
Number 17
VOL. 17 (1), 2014
Number 16
VOL. 16 (2), 2013
Number 16
VOL. 16 (1), 2013
Number 15
VOL. 15 (2), 2012
Number 15
VOL. 15, 2012 Supplement
Number 15
Vol. 15 (1), 2012
Number 14
14 - Vol. 14 (2), 2011
Number 14
The 9th Balkan Congress of Medical Genetics
Number 14
14 - Vol. 14 (1), 2011
Number 13
Vol. 13 (2), 2010
Number 13
Vol.13 (1), 2010
Number 12
Vol.12 (2), 2009
Number 12
Vol.12 (1), 2009
Number 11
Vol.11 (2),2008
Number 11
Vol.11 (1),2008
Number 10
Vol.10 (2), 2007
Number 10
10 (1),2007
Number 9
1&2, 2006
Number 9
3&4, 2006
Number 8
1&2, 2005
Number 8
3&4, 2004
Number 7
1&2, 2004
Number 6
3&4, 2003
Number 6
1&2, 2003
Number 5
3&4, 2002
Number 5
1&2, 2002
Number 4
Vol.3 (4), 2000
Number 4
Vol.2 (4), 1999
Number 4
Vol.1 (4), 1998
Number 4
3&4, 2001
Number 4
1&2, 2001
Number 3
Vol.3 (3), 2000
Number 3
Vol.2 (3), 1999
Number 3
Vol.1 (3), 1998
Number 2
Vol.3(2), 2000
Number 2
Vol.1 (2), 1998
Number 2
Vol.2 (2), 1999
Number 1
Vol.3 (1), 2000
Number 1
Vol.2 (1), 1999
Number 1
Vol.1 (1), 1998

 

 


 About the journal ::: Editorial ::: Subscription ::: Information for authors ::: Contact
 Copyright © Balkan Journal of Medical Genetics 2006