PP 26. OBSERVING WITH FISH METHODS FOR SHORTENING OF TELOMERE WITH ESSENTIAL HYPERTENSION
ONRAT T.S1, Tomatir A.G2 1 Department of Biology , Molecular Biology and Genetics, Afyon Kocatepe University Science Faculty, Afyon, Turkey; 2 Department of Medical Biology, Pamukkale University Medical Faculty, Denizli, Turkey. e-mail: tutgunonrat@yahoo.com
*Corresponding Author:
page: 59

Abstract

In this study; it is aimed to compare of signals with FISH methods between 12p and 15q telomere which are hypertensive persons and normotensive persons. We accepted that the persons who are sistolic blood pressure >140mmHg and diastolic blood pressure >90mmHg, are essential hypertension. These persons have not any cronic illnesses. Age range of  hypertensive and normotensive persons is determined as 45-89. We prepared that metaphases preparates which are based on peripheral blood sample from hypertensive 5 persons and normotensive 5 persons, and we made fluorescence in situ hybridization (FISH) application by using 12p ve 15q  CYTOCELL Telomer Probs. We have completed at study-groups which are applied 12p and 15q telomere probs by FISH methods on hypertensive and normotensive groups. There is no difference between signals of hypertensive and signals of normotensive groups.




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